PRO-LAD

<h1 id="firstHeading" class="firstHeading" lang="en">PRO-LAD</h1>

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<caption>PRO-LAD</caption>

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<td colspan="2" ><a href="http://en.wikipedia.org/wiki/File:PRO-LAD_structure.png" class="image"><img src="/9a3d0350-592f-5de5-9e63-3a6d823864db.png"/></a></td>

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<th colspan="2" >Systematic (<a href="http://en.wikipedia.org/wiki/International_Union_of_Pure_and_Applied_Chemistry_nomenclature" title="International Union of Pure and Applied Chemistry nomenclature" class="mw-redirect">IUPAC</a>) name</th>

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<td colspan="2" >(8β)-<i>N,N</i>-Diethyl-6-propyl-9,10-didehydroergoline-8-carboxamide</td>

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<th colspan="2" >Clinical data</th>

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<div ><a href="http://en.wikipedia.org/wiki/Regulation_of_therapeutic_goods" title="Regulation of therapeutic goods">Legal status</a></div>

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<li>Controlled in the <a href="http://en.wikipedia.org/wiki/United_States" title="United States">United States</a> via the <a href="http://en.wikipedia.org/wiki/Federal_Analog_Act" title="Federal Analog Act">Federal Analog Act</a> but only if it is intended for human consumption.</li>

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<div ><a href="http://en.wikipedia.org/wiki/Route_of_administration" title="Route of administration">Routes of

administration</a></div>

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<td><a href="http://en.wiktionary.org/wiki/oral" class="extiw" title="wiktionary:oral">Oral</a></td>

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<th colspan="2" >Pharmacokinetic data</th>

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<th scope="row" ><a href="http://en.wikipedia.org/wiki/Drug_metabolism" title="Drug metabolism">Metabolism</a></th>

<td>hepatic</td>

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<th scope="row" ><a href="http://en.wikipedia.org/wiki/Excretion" title="Excretion">Excretion</a></th>

<td>renal</td>

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<th colspan="2" >Identifiers</th>

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<div ><a href="http://en.wikipedia.org/wiki/CAS_Registry_Number" title="CAS Registry Number">CAS Registry Number</a></div>

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<td><a rel="nofollow" class="external text" href="http://www.nlm.nih.gov/cgi/mesh/2009/MB_cgi?term=65527-63-1&rn=1">65527-63-1</a>^{&nbsp;<img src="/61e758fe-3c28-5261-9642-2c108f958089.png"/>}</td>

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<th scope="row" ><a href="http://en.wikipedia.org/wiki/PubChem" title="PubChem">PubChem</a></th>

<td><a rel="nofollow" class="external text" href="http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=44457803">CID 44457803</a></td>

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<th scope="row" ><a href="http://en.wikipedia.org/wiki/ChemSpider" title="ChemSpider">ChemSpider</a></th>

<td><a rel="nofollow" class="external text" href="http://www.chemspider.com/Chemical-Structure.21106361.html">21106361</a>^{&nbsp;<img src="/561a9ef4-06e4-5858-8c83-a0d6351eb9a0.png"/>}</td>

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<th scope="row" ><a href="http://en.wikipedia.org/wiki/ChEMBL" title="ChEMBL">ChEMBL</a></th>

<td><a rel="nofollow" class="external text" href="https://www.ebi.ac.uk/chembldb/index.php/compound/inspect/CHEMBL22258">CHEMBL22258</a>^{&nbsp;<img src="/58a56bae-853d-5046-ac60-f06df199b4e4.png"/>}</td>

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<th scope="row" ><a href="http://en.wikipedia.org/wiki/Synonym" title="Synonym">Synonyms</a></th>

<td><small>PRO-LAD,

6-propyl- 6-nor- Lysergic acid diethylamide,

(6a<i>R</i>,9<i>R</i>)- <i>N,N</i>- diethyl- 7-propyl- 4,6,6a,7,8,9- hexahydroindolo- [4,3-<i>fg</i>] quinoline- 9- carboxamide</small></td>

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<th colspan="2" >Chemical data</th>

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<th scope="row" ><a href="http://en.wikipedia.org/wiki/Chemical_formula" title="Chemical formula">Formula</a></th>

<td><a href="http://en.wikipedia.org/wiki/Carbon" title="Carbon">C</a>₂₂<a href="http://en.wikipedia.org/wiki/Hydrogen" title="Hydrogen">H</a>₂₉<a href="http://en.wikipedia.org/wiki/Nitrogen" title="Nitrogen">N</a>₃<a href="http://en.wikipedia.org/wiki/Oxygen" title="Oxygen">O</a></td>

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<div ><a href="http://en.wikipedia.org/wiki/Molecular_mass" title="Molecular mass">Molecular mass</a></div>

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<td>351.50 g/mol</td>

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<div class="NavHead" ><a href="http://en.wikipedia.org/wiki/Simplified_molecular_input_line_entry_specification" title="Simplified molecular input line entry specification" class="mw-redirect">SMILES</a><a href="http://en.wikipedia.org/wiki/PRO-LAD#" id="NavToggle1" class="NavToggle">[show]</a></div>

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<div class="NavHead" ><a href="http://en.wikipedia.org/wiki/International_Chemical_Identifier" title="International Chemical Identifier">InChI</a><a href="http://en.wikipedia.org/wiki/PRO-LAD#" id="NavToggle2" class="NavToggle">[show]</a></div>

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<th colspan="2" >&nbsp;<img src="/99dbb813-daea-5ac2-b58f-7be5b6393da9.png"/>&nbsp;<a href="http://en.wikipedia.org/wiki/Wikipedia:WikiProject_Chemicals/Chembox_validation" title="Wikipedia:WikiProject Chemicals/Chembox validation">(what is this?)</a>&nbsp;&nbsp;<a class="external text" href="http://en.wikipedia.org/w/index.php?title=Special:ComparePages&rev1=417615822&page2=PRO-LAD">(verify)</a></th>

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<p><b>PRO-LAD</b> is an analogue of <a href="http://en.wikipedia.org/wiki/LSD" title="LSD" class="mw-redirect">LSD</a>. It is described by <a href="http://en.wikipedia.org/wiki/Alexander_Shulgin" title="Alexander Shulgin">Alexander Shulgin</a> in the book <a href="http://en.wikipedia.org/wiki/TiHKAL" title="TiHKAL">TiHKAL</a>. PRO-LAD is a <a href="http://en.wikipedia.org/wiki/Psychedelic_drug" title="Psychedelic drug">psychedelic drug</a> similar to LSD, and is around as potent as LSD itself with an active dose reported at between 100 and 200 micrograms.<sup id="cite_ref-pmid4032428_1-0" class="reference"><a href="http://en.wikipedia.org/wiki/PRO-LAD#cite_note-pmid4032428-1">[1]</a></sup>

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<h2>Contents</h2>

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<li class="toclevel-1 tocsection-1"><a href="http://en.wikipedia.org/wiki/PRO-LAD#Legal_Status">1 Legal Status</a></li>

<li class="toclevel-1 tocsection-2"><a href="http://en.wikipedia.org/wiki/PRO-LAD#Literature">2 Literature</a></li>

<li class="toclevel-1 tocsection-3"><a href="http://en.wikipedia.org/wiki/PRO-LAD#See_also">3 See also</a></li>

<li class="toclevel-1 tocsection-4"><a href="http://en.wikipedia.org/wiki/PRO-LAD#References">4 References</a></li>

<li class="toclevel-1 tocsection-5"><a href="http://en.wikipedia.org/wiki/PRO-LAD#External_links">5 External links</a></li>

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<p>&nbsp;</p>

<h2>Legal Status</h2>

<p>On June 10th 2014 the UK <a href="http://en.wikipedia.org/wiki/Advisory_Council_on_the_Misuse_of_Drugs" title="Advisory Council on the Misuse of Drugs">Advisory Council on the Misuse of Drugs</a> (ACMD) recommended that LSZ be specifically named in the <a href="http://en.wikipedia.org/wiki/UK_Misuse_of_Drugs_Act" title="UK Misuse of Drugs Act" class="mw-redirect">UK Misuse of Drugs Act</a> as a class A drug despite not identifying it as ever having been sold or any harm associated with its use.<sup id="cite_ref-ACMD_tryptamines_2-0" class="reference"><a href="http://en.wikipedia.org/wiki/PRO-LAD#cite_note-ACMD_tryptamines-2">[2]</a></sup> The UK Home office accepted this advice and announced a ban of the substance to be enacted on 6 January 2015 as part of <a rel="nofollow" class="external text" href="http://www.legislation.gov.uk/uksi/2014/3271/made">The Misuse of Drugs Act 1971 (Amendment) (No. 2) Order 2014</a>.</p>