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Triple Helix Discovery Engine
Pneumonia, Pneumococcal
Children
*Architects: Pneumonia, Pneumococcal
*Health Recovery Solutions helps reduce readmissions (Congestive Heart Failure, Heart Attack, Pneumonia, Diabetes, COPD) for hospitals and ACOs through a mobile and cloud based early warning system.
*Its lead candidate, CMTX-101, is a humanized monoclonal antibody in preclinical development for hospital-acquired pneumonia.
*Its lead vaccine candidate is VAX-24, a 24-valent investigational pneumococcal conjugate vaccine.
*Pioneers: Infectious Diseases _ Pneumonia
*The company also develops VAX-XP to protect against emerging strains causing significant invasive pneumococcal disease and antibiotic resistance
$70,000 --U.S. Navy Phase 1 STTR contract: Acinetobacter (Wound, dysentery, pneumonia)
2011: GAVI Alliance to Fund Rotavirus and Pneumococcal Vaccines in Thirty-Seven Countries (2011)
2011: Nanotechnology firm Liquidia partners with PATH on new pneumonia vaccine (2011)
2017: MTEC_Host-targeted Immune Stimulation by PUL-042 for Prevention of Pneumonia in a Ferret Model of the Damaged Lung
2017: Paratek is developing omadacycline in adult communiy acquired bacterial pneumonia
2018: Arsanis to discontinue Phase 2 trial of pneumonia treatment_seekingalpha.com
2018: Pulmotect, Inc. (Houston, Texas) - $291,462_Prevention of Pneumonia in a Ferret Model of the Damaged Lung (MTEC)
2021: Gates Foundation to invest up to $90 million in pneumococcal vaccine
2021: Paratek Pharmaceuticals, Inc. (NASDAQ:PRTK) shares closed the week up 17% to $9.60 following news the FDA approved its supplemental New Drug Application (sNDA) for the oral-only dosing regimen of NUZYRA for the treatment of adults with Community-Acquired Bacterial Pneumonia (CABP).
2022: GSK gets pneumococcal vaccine contender with $2.1B Affinivax acquisition
2022: NHLBI_ARDS, Pneumonia, and Sepsis Phenotyping Consortium Clinical Centers (U01 Clinical Trial Not Allowed)
2022: NIAID_Partnerships for Rapid Diagnostics and Phenotypic Antibacterial Susceptibility Testing for Bacteremia or Hospital Acquired Pneumonia (R01 Clinical Trial Not Allowed)
2026: A breath test could diagnose pneumonia in minutes _ www.technologyreview.com
3) Yield positive impact data on the relationships between PACS and radiology indicators for community-acquired pneumonia, strok
Affinivax
Aspisafe Solutions' flagship product is a nasogastric tube that prevents stomach reflux that reduces the chances of pneumonia.
Backed by the private equity firm Perseus, the company is pursuing treatments for herpes labialis (cold sores), onychomycosis (nail fungus), acne, cystic fibrosis and mucosal vaccines for influenza, pneumococcal infections and RSV.
Boston University Medical Campus Mobile Bedside Ultrasound for the Diagnosis of Pediatric Pneumonia in Resource Limited Settings (Zambia)
Clinical-stage small molecule drug discovery company developing antiinfectives against community acquired pneumonia, chronic bronchitis and complicated skin infections
Genocea will use funds to advance its deep research pipeline, including prophylactic vaccine programs addressing Chlamydia trachomatis, Streptococcus pneumoniae, HSV-2 and Plasmodium falciparum (malaria).
Its medical device is designed for several triggers, including pneumonia or trauma.
Klebsiella pneumoniae
Next generation Pneumococcal bioconjugate vaccine, (2) multivalent Klebsiella pneumoniae bioconjugate vaccine, and (3) a comprehensive Group B Streptococcus bioconjugate vaccine.
Novel anti-Pneumococcal Preparations-Children's Hospital Boston
Novel Pneumococcal Vaccine with Adjuvant Properties-Children's Hospital Boston
NUZYRA (omadacycline) is a broad spectrum, novel antibiotic with both once-daily intravenous and oral formulations for the treatment of community-acquired bacterial pneumonia and acute bacterial skin and skin structure infections
Offers long lasting protection from bacteria (e.g., pneumonia) and viruses (e.g., HIV) without promoting the emergence of microb
The other vaccine, Prevnar, licensed to Wyeth Pharmaceuticals, prevents pneumococcal bacteria that can cause meningitis.