Specifically, this FOA will support studies that: 1) clarify social, economic, behavioral, and institutional explanations for place-based health disparities (levels and trends), 2) examine intersections between place and sociodemographic characteristics (e.g., gender, race, ethnicity) to better understand and address processes driving other health disparities, and/or 3) include data collection and data enhancements to support 1 and 2.