MedTechIQ_3Helix InSight Engine-Beta
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Triple Helix Discovery Engine
Triple Helix Framework
Industry
Architects: Small & Medium Size Business (SMBs), Product Development, De-Risking, Validation, Building Niche & Emerging Markets
*Architects: Gastroenterology_Gastrointestinal (to include Liver, Pancreas & metabolic dysfunction-associated steatotic liver disease (MASLD), Gout, MASH (Metabolic dysfunction-associated steatohepatitis), formerly, NASH (Non-Alcoholic SteatoHepatitis)Non-Alcoholic SteatoHepatitis (NASH)
Fractyl Laboratories
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Fractyl | Innovative Clinical Procedure to Treat Metabolic Disease
Parents
*Architects: Diabetes, Dialysis, Renal & Kidney Disease Companies (Health IT, Devices & Technology)
*Architects: Gastroenterology_Gastrointestinal (to include Liver, Pancreas & metabolic dysfunction-associated steatotic liver disease (MASLD), Gout, MASH (Metabolic dysfunction-associated steatohepatitis), formerly, NASH (Non-Alcoholic SteatoHepatitis)Non-Alcoholic SteatoHepatitis (NASH)
*Architects: Surgical Technology_Endoscopes & Laproscopes
*Industry: Massachusetts
Portfolio Companies: Catalio
Venture Capital: Series E
Children
2020: Financing led by Taiwania Capital Management Corporation, with Bessemer Venture Partners, General Catalyst, Domain Associates, Mithril Capital Management, Emergent Medical Partners, True Ventures, GV. Catalio Capital Management, CDIB Venture Capital Corp., and YJ Capital, 2020: Fractyl Raises $55 Million in Series E Financing to Advance Revita DMR for Type 2 Diabetes
2020: Fractyl nets $55M for intestine-resurfacing trial in Type 2 diabetes
2020: Fractyl Raises $55 Million in Series E Financing to Advance Revita DMR for Type 2 Diabetes
Founded 2011
Lexington, Massachusetts
The company was founded by Dr. Harith Rajagopalan and Jay Caplan.
The Revita DMR treatment harnesses breakthrough insights in intestinal biology and aims to reset key metabolic pathways, including insulin resistance, to reverse metabolic disease.
This same-day, outpatient endoscopic procedure uses heat to resurface the lining of the upper intestine (duodenal mucosa) in a minimally invasive, outpatient procedure.