Drug Discovery & Development Process Optimization

Parents

*Driving Forces: BioPharmaceuticals _ Biotechnology, Genomics, Genetics, Bioinformatics, Biomanufacturing & Personalized Medicine, Drug Discovery, Development & Delivery
*Driving Forces: Pharmaceuticals, Clinical Trials, CROs, CDMOs & Pharmacovigilance
1. Technology Transfer (T2):Services:Industry
Calibrant Biosystems, Inc.
Drug Discovery
Drug Discovery Technologies
Genova Biosciences, Inc
Intradigm Corporation
MEMS customers
National Functional Genomics Center (NFGC):Research Areas
Technology Transfer (T2):Business Development

*Pioneers: Bioluminescence Imaging
*Systems Biology-Levels of Biological Information
>13% FDA success rate from preclinical cancer drug candidate to FDA approval
1. Fundamental Biology
3. Structural Biology & Medicinal Chemistry
4. Drug Design
5. Drug Hit
6. Drug Trials
7. Drug Launch
Biomarker, target discovery, target validation, preclinical trial
Molecular imaging is the in vivo visualization of cellular processes at the molecular level
Promising, yet inadequate current approaches to protein based drug development