Amide Functional Group

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Amides are a common and useful organic functional group consisting of a carbon, oxygen, and nitrogen atom. In this article, the structure, atomic properties, synthesis, reactions, and role in peptide bonding of the amide functional group are explored.

Amides are most structurally similar to carboxylic acids, which have a second oxygen in place of the nitrogen. Amides are also similar to amines, which consist of only a nitrogen atom bonded to at least one carbon atom.