Adenovirus type 7

Parents

1960s Live types 4 and 7 adenovirus vaccines, given as enterically coated capsules, were developed in the middle 1960s, under the leadership of COL Edward Buescher (Fig. 5), and were extensively studied at military facilities.42
1971-1996 As a result of adenovirus vaccine use during the period from 1971 to 1996, essentially no outbreaks in military units of ARD related to either of the adenovirus serotypes used in the vaccines were reported.
1996-1998 Recent surveillance data from sentinel military populations revealed that 55% of throat cultures obtained from recruits with ARD between 1996 and 1998 yielded adenoviruses, largely types 4 and 7.30
Outbreaks of adenovirus infection causing ARD have been reported for a variety of military centers since the cessation of routine vaccination and have generally resulted from...
Subsequent studies demonstrated that adenovirus types 4 and 7 accounted for the majority of ARD cases among recruits.39
The products, given either singly or in combination, were found to be safe, immunogenic, and highly protective, resulting in a 50% decrease in the rate of hospitalization attributable to ARD among recruits and a more than 95% reduction in...