Kopito Lab Ron
<p>May 05, 2015 09:43 PM</p>
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see his talk today at Protein QC conf. in LKS.</p>
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intracell... protein conc. > 200 mg/ml.</p>
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newly synth proteins achieve their 3d struc by "foldin" within tis highly dynamic jungle.</p>
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cells must ensure that those proteins that FAIL to FOLD are effic disposed of....
or suffer the conseuqences.</p>
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Misfolded proteins are toxic to cells. cause Alzh, Huntingtons, Pkson dis...
and cystic fibrosis etc.</p>
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Our lab: how are misfolded proteins detected and destroyed by QC pathways...
Ub-proteasome and autophagy systems</p>
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