Appendix A of BRAIN 2025
<p>Jul 25, 2014 06:08 PM</p>
<p>
5M Americans with Alzheimers. cost is 200B per year including 150B from Medicare/caid.</p>
<p>
2.4M Americ: schiz;</p>
<p>
we need better understanding of brain circuits and networks;</p>
<p>
ex: ion channelopathies => seizure.</p>
<p>
Pkson: degen of DA neurons</p>
<p>
ECT: fastest acting and most effective rx for depression; but we seek DBS rx of depression: more focal
and rational circuit based intervention;
need gen of implantable devices;</p>
<p>
Neuromodulation: impants began with cardiac pacers.
DBS success for Pkson and rigidity for basla ganglia disorders.</p>
<p>
Epilepsy: intacvtable sx; early detection of sz and turn it off before it starts;</p>
<p>
Resotre lost vision! thru optogenetics; cortical or retinal prostheses;</p>
<p>
</p>