2016 VA High-intensity Statins Benefit Elderly CAD
<p>Nov 11, 2016 01:17 PM pub in JAMA Cardiology.</p>
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half million veterans with estab ASCVD </p>
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even subgroup from 76 to 84 had a survival benefit comparable to younger patients age 21 to 75.</p>
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adjusted HR of 0.91.</p>
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this is for secondary prevention.</p>
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senior author Paul Heidenreich at Stanford</p>
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current VAH and US DoD recomm moderate dose (10 to 20) and then titrate up to high dose = 40 to 80 of atorvastatin.</p>
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Overall, statin intensity was associated with mortality in a stepwise manner, with 1-year mortality rates of 4.0%, 4.8%, 5.7%, and 6.6% in patients receiving high-, moderate-, and low-intensity statins or no statin therapy.</p>
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