Open in TheBrain

GONZALEZ, Alexander, Parietal Cortex Memory Encoding, Wagner Lab, Jan 11, 2016

<p class="MsoNormal" >GONZALEZ, Alexander, Parietal Cortex Memory Encoding,&nbsp; Wagner Lab, Jan 11, 2016

This is a talk at the MBC grad training program on Monday at Stfd.

He is a grad student in Anthony Wagner's Lab.</p>

<p>

.he shows kid with light saber&nbsp; (why so memorable?&nbsp; eg)</p>

<p>

episodic memory..</p>

<p>

PFC exerts&nbsp; exec control that selects info in WM that comprises&nbsp; episodic memory.</p>

<p>

how abt&nbsp; parietal cortex...</p>

<p>

he shows&nbsp; Lateral parietal cortex...</p>

<p>

shows&nbsp; buckner, krienen 2013 slide...&nbsp;&nbsp; networks that involve&nbsp; par. lobe.</p>

<p>

outline for today</p>

<p>

encoding activity in parietal cortex&nbsp;&nbsp; and encoding behavior</p>

<p>

and 2)&nbsp; encoding activity&nbsp; and retrieval behavior...</p>

<p>

shows raw LFP&nbsp; over&nbsp; 2000 msec&nbsp; in HC.</p>

<p>

if get big&nbsp; negative fluctuation then get good encoding.</p>

<p>

see lower freq deactivated and higher freq activated during&nbsp; encoding...</p>

<p>

so,&nbsp; PPC activity during encoding...</p>

<p>

model is that</p>

<p>

greater DORSAL PPC activity&nbsp; is corr with subseq memory success</p>

<p>

cuz that&nbsp; is correl with <b>top down&nbsp; goal directed attention</b>&nbsp; during the encoding...</p>

<p>

in contrast&nbsp; ventral&nbsp; PCC... activ&nbsp; is negat. correl with memory retr success.</p>

<p>

shows trode coverage&nbsp; (in ECoG pts)</p>

<p>

task....</p>

<p>

see words... did you see it or not?&nbsp; measured by RT if successful.</p>

<p>

x axis is time&nbsp; over&nbsp; abt&nbsp; 1.5 seconds

and y axis is&nbsp;&nbsp; freq power...</p>

<p>

blue&nbsp; means&nbsp;&nbsp; decr in&nbsp; that freq band...</p>

<p>

he compares&nbsp; SPL&nbsp; super parietal lobe&nbsp; vs&nbsp; IPS&nbsp; = intraparietal sulcus...</p>

<p>

these areas are quite active during encoding...</p>

<p>

higher&nbsp;&nbsp; activity in HGP&nbsp;&nbsp; high gamma band&nbsp;&nbsp; leads to faster RTs.</p>

<p>

faster RTs&nbsp; =>&nbsp; more confidence in memory.</p>

<p>

then used&nbsp; elasstic-net regression penalization on all freq bands...</p>

<p>

summary</p>

<p>

dorsal PPC activity predicts semantic decision RT...</p>

<p>

&nbsp;

&nbsp;</p>

Attachments