Selegiline

<p>Dec 16, 2013 09:12 PM</p>

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see lecture tonite by Steve Fowkes at Health Activator &nbsp;(Christine P hosts);</p>

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rx early stage Pkson Dis = PD, depression, and dementia.</p>

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selective irrev MAO-B inhibitor. &nbsp;(in large doses also inhibs MAO-A.</p>

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no dietary restric with low doses.</p>

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a levomethoamphet deriv with a propargyl group.</p>

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2006 &nbsp;being tested for rx of ADHD.</p>

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primary metabs: &nbsp;L amphet and L methamphet... mild sympath side effects.

both had + effects for memory enhancement in rats.</p>

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molecule is fat soluble...&nbsp;

low oral bioavail. &nbsp;incr to moderate with a high-fat meal.</p>

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