Glagov phenomenon
<p>September 29, 2020, 12:15 PM orig pub 1987 by Glagov.</p>
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<p><strong>Glagov phenomenon</strong> denotes the adaptive enlargement of <a class="mw-redirect" title="Coronary artery" href="https://www.wikidoc.org/index.php/Coronary_artery">coronary artery</a> in response to <a title="Plaque" href="https://www.wikidoc.org/index.php/Plaque">plaque</a> formation. Lumen area is preserved during the early stage of <a class="mw-redirect" title="Coronary artery disease" href="https://www.wikidoc.org/index.php/Coronary_artery_disease">coronary artery disease</a> and lumen encroachment becomes evident until the lesion occupies greater than 40% of the <a title="Internal elastic lamina" href="https://www.wikidoc.org/index.php/Internal_elastic_lamina">internal elastic lamina</a> area.<sup id="cite_ref-Glagov-1987_1-0" class="reference"><a href="https://www.wikidoc.org/index.php/Glagov_phenomenon#cite_note-Glagov-1987-1">[1]</a></sup> Thus, angiography-detectable stenosis and significant functional impairment may be delayed despite the presence of a fairly sizable <a class="mw-redirect" title="Atherosclerotic plaque" href="https://www.wikidoc.org/index.php/Atherosclerotic_plaque">atherosclerotic plaque</a>.</p>
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