CLL Chronic Lympocytic Leukemia Lymphoid
<p>Mar 10, 2017 01:42 PM</p>
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affects b-cell lymphs. (which produce antibodies)</p>
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accumulate in marow and blood and crowd out healthy blood cells.</p>
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CLL is a stage of SLL = small lymphocytic lymphoma.</p>
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63% in men... usu in elderly.</p>
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most have no sxs;
can result in swollen nodes, spleen, liver and eventually anemia and infections.</p>
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if + for ZAP-70 then 8 year survival;
if - for ZAP-70 then > 25 yr survival.</p>
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usu dx if lymphs > 4000 per cubic mm.</p>
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find CD5 and CD23... and from a single clone
see only a single light chain either kappa or lampbda.</p>
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what is the stage: is there lymphadenopathy?
is there incr spleen or liver
is higb decreased or plates dec.</p>
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