Hasselmo, Michael

<p>Jun 09, 2015 12:02 PM</p>

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D Phil Oxford.</p>

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directs &nbsp;Comp Neurophys Lab at BU.</p>

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faculty: &nbsp;Center for Memory and Brain</p>

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Research in my laboratory concerns the <b>cortical dynamics of memory-guided behavior,</b>&nbsp;

including effects of <b>neuromodulatory receptors</b> and

the role of <b>theta rhythm oscillations</b> in cortical function.</p>

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Neurophysiological techniques are used to analyze intrinsic and synaptic properties of cortical circuits in the <b>rat</b>, and to explore the <b>effects of modulators</b> on these properties.&nbsp;</p>

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<b>Computational modeling</b> is used to link this physiological data to memory-guided behavior.</p>

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Experiments using multiple single-unit recording in behavioral tasks are designed to test predictions of the computational models.&nbsp;</p>

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Areas of focused research include <b>episodic memory function</b> and

<b> theta rhythm dynamics in the entorhinal cortex</b>,&nbsp;

<b>prefrontal cortex and hippocampal formation</b>.</p>

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Research addresses physiological effects relevant to&nbsp;

Alzheimer’s disease, schizophrenia and depression.</p>