Leukotriene
<p>Jul 21, 2011 01:14 PM
 
Correct pronunciation is l<b>euko  TRY een</b>   (confirmed in video)
 
word comes from  leuko as in leukocytes and the TRIENE refers to the three conjugated double bonds
 
used to be called  SRS-A  =  slow reacting substance of anaphylaxis.
 
fatty signaling molecules.
 
first found in leukocytes.
 
produces  smooth mus tightening,  inflam in ashtma and allergic rhinitis  (specifically leukotriene D4)
 
LT = leukotrienes are natural  eicosanoid  lipid mediators.
 
LT are produced from  arachidonic acid  (usu they r produced accomp by histamine)
 
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