2016 Dec Daniel Palanker SCIEN Electro Interfaces
<p>Jan 10, 2017 08:43 PM</p>
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intro by Joyce Farrell;</p>
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Daniel is also Direc of Hansen Lab.</p>
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spike: 1 ms duration and 100 mV.</p>
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Q = 106 ions.</p>
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pacemaker, since 1958....</p>
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modern pacemaker... can be inserted IV; wireless;</p>
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myoelectric signals....from Chalmers Univ in Sweden... great videos... of
hand and fingers.</p>
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Deka Arm...</p>
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Bebionic... from RSL Steeper... excellent!!!</p>
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Micromo... v fast gait!</p>
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kicking soccer ball; 4 mph gait;
records from just a few trodes on skin.</p>
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BrainGate2 Kathy Hutchinson... Shenoy Lab</p>
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Utah array...</p>
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EPFL walking in monkey... walking on treadmill.</p>
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foot off and foot strike. wow!!! restores broken connection!!!</p>
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Gregoire Courtine EPFL Nature p 284 2016 get this!</p>
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restores gait!!!</p>
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turns on machine 6 days after injury of cord. with</p>
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wireless brain spine interface.</p>
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easier to read out the muscle (rather than nerves)</p>
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redirect nerves to chest... now can read out muscles in chest
to activate</p>
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picks up coffee cup and can bounce ball and grad cloth... DARPA
target reinnervation.... long video a TED video.
control is v intuitive.</p>
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need tactile sensitivity:</p>
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can also use afferent nerves. reimplant them</p>
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and blood vessels:</p>
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can constrict vessel eg for trauma to leg.</p>
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and tear secretion...</p>
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oculeve....implant to lacrimal gland. RF xmission and tears secreted...
worked in rabbits...</p>
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afferent nerves... can activate N from nose... touch muscoas in nose...
secreted tears... TearBud by Oculeve.
3X per day... Allergan.</p>
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DBS for Parkinsons....</p>
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disables overactive nerve cells in thalmus.</p>
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now turns off controller....</p>
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massive tremor in both hands and speech is ataxic... terrib le dystonia.</p>
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and twisting in neck....</p>
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eliminating patholog synchrony...</p>
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apply random phase to retrain system.</p>
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TMS:</p>
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TDCS: Trends in Neurosci...</p>
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Vagus N stim: for epilepsy and depression:
stim using a magnet on wrist... to stim vagus</p>
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or use transcutaneous...</p>
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Cochlear implant aud N has 30K fibers divided into 24 channels</p>
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12 to 20 trodes enuf.</p>
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today > 250K implants world worldwide.</p>
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recent upgrade for partial hearing loss
say only 10 mm deep to just restore high freq hearing most superficial cochlea just 10 mm.</p>
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takes 10 months to adapt...</p>
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JRRD 2008....</p>
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Brian asks abt how freq a good result is achieved with cochlea;</p>
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partial implant is becoming a reality...</p>
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digital taste simulator.</p>
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restoring memory....</p>
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Argus II RGCs...</p>
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Retinal Implant AG... 20/1200</p>
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but now 2 more pts with 20/550...</p>
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bright IR light</p>
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each is 70 micron and has 20 micron trodes
can fit in 4800 pixels.</p>
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local return trodes...</p>
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at 905 nm....</p>
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nl vision 30 microns....
our system 67 microns... can see as much as we can deliver...</p>
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rabbits and Long-Evans rats...</p>
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use visual evoked potentials...</p>
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grating VA vis acuity .... signal synchronized to motion if rat can see it...
it gets 64 microns...
will be acuity of 20 over 256 and may even get to 20/200 in humans....</p>
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contrast sensiti is 12% with system....</p>
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and now will get to 55 microns and then to 40 microns...
should get 10,000 pixels!!! (at 40 microns....</p>
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perhaps artific senses...</p>
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eg seeing mag fields.</p>
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rat could learn to orient with magnet fields.</p>
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