p53 Tumor Suppressor Gene

<p>Oct 10, 2016 09:22 PM</p>

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and Dec 20, 2018 10:59 PM</p>

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tumor suppressor gene.... &nbsp;&nbsp;it stops formation of tumors.</p>

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discov &nbsp;1979 &nbsp;&nbsp;located on &nbsp;chromo 17p13</p>

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p53 protein is the product of the p53 gene. &nbsp;53 kilo dalton...</p>

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regulation of cell cycle; &nbsp;DNA repair and &nbsp;apoptosis.</p>

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prevents caner by cell cycle arrest or by triggering apoptosis.</p>

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any form of DNA damage triggers &nbsp;p53 gene.</p>

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it prevents cell from entering &nbsp;S phase.</p>

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hence &nbsp;... arrest of cell cycle at G1 phase.</p>

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that allows time for DNA repair. &nbsp;(during S phase.</p>

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and p53 &nbsp;induces DNA repair.</p>

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