COURAGE: Revascularization and Aggressive Drug Evaluation
<p class="default">04:27 PM, June 18, 2007
 
Courage: total of 2287 patients at 50 centers in US and Canada.
All pts got ASA or clopidogrel and all got simvastatin and/or zetia.
Mean follow-up was 4.6 years.
 
Average age 62 years old
85% men
look at table 1: 1/3 of patients had previous bypasses or PCI's etc.
This study was for stable coronary disease.
Death during study was only 8%.
Non fatal MI rate was 11%.
1/3 were diabetic
2/3 had HTN
40% had prior MI.
One third has prox LAD disease (> 70% stenosis)
and 1/3 had 3 vessel disease.
 
Result: NO difference btwn PCI + OMT vs OMT (optimal med therapy).</p>