Open in TheBrain

Caloric restriction improves memory... [Proc Natl Acad Sci U S A. 2009]

<p>Oct 19, 2011 10:00 PM &#160;great study! &#160;&#160;open access, full text !

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average bmi was 28 in this group. &#160;&#160;avg age 60.5

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50 subjects;

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3 months of intervention...

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signif incr in verbal memory score = + 20% !!!! p &#60;.001

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from Univ of Munster.

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by Witte, Fobker, Gellner et al &#160;in &#160;PNAS 2009.

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note: &#160;no change in the group that simply incr % of UFAs

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CONCLUSION: &#160;this is the <b>FIRST empirical evidence for the effect in humans</b>:

<b>CR improves memory in the elderly</b> !

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incr insulin sensitivity and reduced inflam activity as mediating mechs =&#62; higher synaptic plasticity and stim of

neuroprotective pathways.

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