Open in TheBrain

Selenium

<p class="default">07:43 PM, November 25, 2007</p>

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from Harvard Health Letter Oct 2007</p>

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purpose of the Nutritional Prevention of Cancer trial

was to test whether taking the mineral &#160;<b>selenium</b> might

protect people against the two most common types of

skin cancer. Taking the 200-microgram (mcg) pills daily

flopped for skin cancer prevention, but when researchers

started to poke around in the data looking for other effects,

they made a pleasant discovery: Men who had taken the

selenium pills seemed to gain some protection against

&#160;<b>prostate cancer</b> . &#160;<b>Compared with the placebo group, the</b>

<b>selenium takers were 63% less likely to have developed</b>

<b>the cancer.</b>

Researchers can find some intriguing associations in

any set of data if they rummage around enough. &#160;<b>&#160;But results</b>

<b>from a variety of other studies have burnished selenium?s</b>

<b>reputation as a prostate cancer preventative.</b>

The final word on selenium will probably come from

the &#160;<b>National Cancer Institute?s Selenium and Vitamin E</b>

<b>Cancer Prevention trial, a huge 35,000-man study that is</b>

<b>testing selenium and vitamin E as a combination</b> , as well

as each by itself. Interim results could be reported earlier,

but the study is not scheduled to be completed for several

years.</p>

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Several years ago, researchers decided to take yet another

look at the data from the nutrition prevention trial. This

time, though, they zeroed in on diabetes, not cancer. The

results, reported in the Aug. 21, 2007, issue of the &#160;<i>Annals of</i>

<i>Internal Medicine,</i> showed that the people (three-quarters

of whom were men) in the study who took selenium pills

were about 50% more likely to have developed diabetes

than those who took the placebo pills.

The absolute risk was pretty small: 39 of the 659 people

in the placebo group (6%) versus 58 of the 653 taking selenium

(9%). Increase a small risk by 50% and you still have

a relatively rare event.

Still, if the jury is still out on selenium?s prostate benefits,

why should men invite more trouble than they have to?

The American Cancer Society?s latest recommendations

for preventing prostate cancer include eating five or more

servings of vegetables and fruit a day, limiting the amount

of red meat and dairy food you eat, staying active, and

keeping off the extra pounds. They aren?t very exciting, but

they?re not going to give you diabetes, either.</p>

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ghghg</p>

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