Targeting

Targeting nanoparticles for better diagnosis and therapy in cancer is a popular idea. However, recent literature shows that only about 0.7% (median) of administered nanoparticle doses reach solid tumors (refer to Figure Targeting) [2016 Wilhelm].

Figure Targeting: Today, targeted nanoparticle delivery is not very efficient. An analysis of the nanomedicine literature reveals small differences in median particle delivery efficiencies over time, by targeting method, and by size. Data from 2016 Wilhelm.