4. Obesity and the Regulation of Body Mass

Adipose Tissue Has Important Endocrine Functions

Leptin Stimulates Production of Anorexigenic Peptide Hormones

Leptin Triggers a Signaling Cascade That Regulates Gene Expression

Adiponectin Acts through AMPK to Increase Insulin Sensitivity

AMPK Coordinates Catabolism and Anabolism in Response to Metabolic Stress

The mTORC1 Pathway Coordinates Cell Growth with the Supply of Nutrients and Energy

Diet Regulates the Expression of Genes Central to Maintaining Body Mass

Short-Term Eating Behavior Is Influenced by Ghrelin, and Cannabinoids

Microbial Symbionts in the Gut Influence Energy Metabolism and Adipogenesis