5. Regulatory Enzymes

• Allosteric Enzymes Undergo Conformational Changes in Response to Modulator Binding

• The Kinetic Properties of Allosteric Enzymes Diverge from Michaelis-Menten Behavior

• Some Enzymes Are Regulated by Reversible Covalent Modification

• Phosphoryl Groups Affect the Structure and Catalytic Activity of Enzymes

• Multiple Phosphorylations Allow Exquisite Regulatory Control

• Some Enzymes and Other Proteins Are Regulated by Proteolytic Cleavage of an Enzyme Precursor