EXC CRITERIA

Participants are excluded if they:

• Have alveolar hemorrhage needing invasive ventilation expected to last beyond screening.

• Have other multisystem autoimmune diseases.

• Have had:

• Dialysis or plasma exchange within 12 weeks before screening.

• Kidney transplant.

• CYC within 12 weeks or RTX within 12 months prior to screening.

• Are on oral glucocorticoids >10 mg/day prednisone (or equivalent) for over 6 consecutive weeks before screening.