Alternative Splicing
<p><b>Alternative splicing</b>, or differential splicing, is a regulated process during gene expression that results in a single gene coding for multiple proteins. In this process, particular exons of a gene may be included within or excluded from the final, processed messenger RNA (mRNA) produced from that gene. Consequently, the proteins translated from alternatively spliced mRNAs will contain differences in their amino acid sequence and, often, in their biological functions (see Figure). Notably, alternative splicing allows the human genome to direct the synthesis of many more proteins than would be expected from its 20,000 protein-coding genes. There are over 100,000 proteins.
 
<img src="/c1b8713e-d554-5d81-a709-0ce5000e853e.png"/>
Alternative Splicing generates transcriptome diversity and provides an opportunity for gene regulation. Alternative splicing can generate mRNAs encoding proteins with different, even opposite functions.
 
 
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