Protein Synthesis
<p><b>Protein synthesis in prokaryotes</b> takes place in the general cytoplasm. In Eukaryotes----the protein synthesis takes place where the ribosomes are located outside the nucleus, since this is the only machinery responsible for this process. This means that the protein synthesis takes place in the cytoplasm, on top of the rough endoplasmic reticulum, in the mitochondria and on the mitochondrial membrane. The protein synthesis definitely does not take place in the nucleus or nucleolus, because as the proteins are macro-molecules, it will be not possible for these protein to leave the nucleus passing through the nucleic envelope.</p>
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<img src="/479b5327-9e64-5060-927c-1219d0643b24.png"/> <img src="/9e8132f8-f411-5cc0-8ea6-d91f5b40039c.png"/> <img src="/42d84550-8c28-5202-bf2d-471df12e7b9f.png"/> </p>
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<img src="/42ba9a96-0226-5488-9a48-124108d8c730.png"/>
For post-Translational instructions see Khan on Protein Targeting for Signal Peptides --these send proteins to the endoplasmic reticulum. Others stay in the Cytosol. But remember that Cytosol and Mitichondria have their own RNA as well. But see general distribution map below.</p>
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<img src="/e4a90163-ee5f-511a-b0f0-f52d35ee5c54.png"/> <img src="/761b71b9-1fca-5166-87e7-4c959a672626.png"/></p>
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