Glutaronitrile
Glutaronitrile, also known as pentanedinitrile, is a nitrile with the formula C₃H₆(CN)₂[1]. It is a chemical compound that has been used in various applications, including cosmetics and personal care products[2]. However, a related compound, methyldibromo glutaronitrile (MDBGN), has been found to cause allergic contact dermatitis reactions in some individuals[4]. MDBGN was commonly used as a preservative in cosmetic and toiletry preparations, but its use was banned in the European Union due to its sensitizing properties[4].
Glutaronitrile itself is a chemical compound of cyanide, and it is listed in the Toxin and Toxin Target Database (T3DB)[5]. It is available for purchase from chemical suppliers, such as Sigma-Aldrich, in various forms and concentrations[3]. The compound has a number of physical and chemical properties, including a melting point of -29°C, a boiling point of 285-287°C, and solubility in water, alcohol, and chloroform[3].
In summary, glutaronitrile is a nitrile compound with a range of properties and uses, while a related compound, methyldibromo glutaronitrile, has been found to cause allergic reactions and has been banned from use in certain applications.
Citations:
[1] https://en.wikipedia.org/wiki/Glutaronitrile
[2] https://www.contactdermatitisinstitute.com/methyldibromo-glutaronitrile-mdbgn.php
[3] https://www.sigmaaldrich.com/IN/en/product/aldrich/130621
[4] https://dermnetnz.org/topics/allergy-to-methyldibromoglutaronitrile
[5] https://pubchem.ncbi.nlm.nih.gov/compound/Glutaronitrile