10 Endothelial Dysfunction and Low Nitric Oxide Production

<p >From: 'Nitric oxide and its possible implication in ME/CFS (Part 2 of 2)' http://phoenixrising.me/archives/25528

This is not the first time that the endothelial dysfunction and&nbsp;<a href="http://www.sciencedirect.com/science/article/pii/016756999290118Q" target="_blank" >nitric oxide production&nbsp;</a>have been implicated within autoimmune diseases. There is evidence of endothelial dysfunction being present in both lupus erythematosus, assorted rheumatic autoimmune diseases, and damage as a consequence of diabetes mellitus. This presents as an increased risk of atherosclerosis and slower wound healing, presumably through the loss of peripheral circulation.

As previously discussed, this increased risk does not at the present time appear to exist within ME/CFS. This prevalence in other diseases does, however, raise the question of whether an immune response targeted towards nitric oxide production could be a secondary mechanism within ME/CFS as seen in these other autoimmune processes.</p>