Hyper State Lower Function
<p>From: <a href="https://academic.oup.com/qjmed/article/93/6/323/1536811">stress response and the hypothalamic‐pituitary‐adrenal axis: from molecule to melancholia | QJM: An International Journal of Medicine | Oxford Academic</a></p>
<p>This stress system is tonically active, but both physical and emotional stressors that exceed a critical threshold increase its activity further. The hypothalamic‐pituitary‐adrenal (HPA) axis and the sympathetic and adrenomedullary (sympathetic) systems are the peripheral limbs of the stress system. Increased system activation as a result of stress leads to central and peripheral changes, which facilitate behavioural adaptation and redirection of energy to the central nervous system, muscle, and stressed body sites. These changes serve to promote homeostasis. HPA axis activation results in glucocorticoid secretion. The principal role of glucocorticoids during the stress response is thought to be restraint of the effectors of the stress response.</p>
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