Lesions
<p>From: <a href="https://www.healthrising.org/blog/2015/11/27/fatigue-multiple-sclerosis-chronic-fatigue-syndrome-and-fibromyalgia-is-it-the-same/">The Fatigue in Multiple Sclerosis, Chronic Fatigue Syndrome (ME/CFS) and Fibromyalgia - Is it the Same? - Health Rising</a></p>
<p>ME/CFS and FM patients may have some lesions but not nearly to the extent as MS. Studies suggest, though, that similar parts of the brain that have been associated with increased fatigue are affected in both disorders. </p>