oxycodone (OxyContin, Roxicodone, Proladone, Oxynorm)

<p>From: Reviving the Broken Marionette: Treatments for CFS/ME and Fibromyalgia

Oxycodone is used to treat moderate and severe chronic pain. Some of its analgesic qualities appear to be mediated through the kappa opioid receptor, as opposed to most other opioids which usually act only through the mu opioid receptor.29 The modified release drug Oxycontin is one of the drugs preferred by doctors to treat the pain caused by CFS/ME and fibromyalgia. It only needs to be taken every 12 hours.

Some SSRIs and some other drugs may elevate the plasma levels of oxycodone. The efficacy of oxycodone is poor in the same people who cannot convert codeine to morphine.

Oxycodone is available in the United States, the United Kingdom, Canada, Australia and some other countries. Tablets, capsules, oral solution, suppositories and different extended release forms are available depending on the country. Some formulations also contain acetaminophen (paracetamol) or NSAIDs. In the United States oxycodone is a Schedule II drug, but in most countries it is in the strictest schedule.

Oxycodone is fairly expensive.</p>