Metaxalone (Skelaxin)

<p>From: Reviving the Broken Marionette: Treatments for CFS/ME and Fibromyalgia

Metaxalone acts somewhat similarly to chlorzoxazone, but without the inhibitory effect on nitric oxide production. It is most commonly Sleep aids, tranquilizers and muscle relaxants used for back problems. It is normally taken three or four times a day.

The most common side effects are nausea, stomach upset, drowsiness, dizziness, headache and irritability. Metaxalone can in rare cases cause liver problems, though this appears to be less common than with chlorzoxazone.

Metaxalone is only available in the United States. There is only one tablet size, 800 mg, which may be too much for many people with CFS/ME and fibromyalgia. It is much more expensive than chlorzoxazone.</p>