Magnesium

From: 'Chronic Fatigue Syndrome, A Roadmap for Testing and Treatment' <a href="https://sites.google.com/site/cfstestingandtreatmentroadmap/home">https://sites.google.com/site/cfstestingandtreatmentroadmap/home</a>

either applied transdermally on the skin, or given by injection) can be of benefit in ME/CFS.<a href="http://www.ncbi.nlm.nih.gov/pubmed/1672392" rel="nofollow" target="_blank" >1</a>

From: PhoenixRising user Basillico on 'Types of Magnesium' <a href="http://forums.phoenixrising.me/index.php?threads/types-of-magnesium.51094/">http://forums.phoenixrising.me/index.php?threads/types-of-magnesium.51094/</a>

<blockquote class="messageText SelectQuoteContainer ugc baseHtml" >-Magnesium oxide is the absolute worst (and unfortunately it's the form usually found in cheaper multivitamins) because it doesn't really get absorbed by the body, so it's a waste of time.

-Magnesium sulfate (Epsom Salts) are not good to use internally because of poor bioavailability.

-Magnesium citrate is probably the best bang for your buck, it's fairly bioavailable and usually cheap. Beware though that with magnesium citrate you can easily get diarrhea. I used the NOW brand, although I don't plan to rebuy it since I learned it's made in China.

-Magnesium malate is also good in terms of bioavailability and it's unlikely to cause diarrhea, but I found that at doses of 100% RDA I would get nausea that would last for a few hours. Others may not have this issue. I used the brand Seeking Health.

-Magnesium glycinate, so far, has been one of my favorites. Good bioavailability. I used the Pure Encapsulationsbrand, which has no fillers or garbage ingredients.

-Magnesium threonate is probably my favorite form. It's very bioavailable, it doesn't cause diarrhea or any other side effects, and it works for my purpose: I take it when I get arrythmia and it makes it go away.

All three kinds of magnesium (citrate, glycinate, malate) have been effective in providing relief from the arrhythmia that I get when my magnesium levels get too low. This was, however, all I could get out of the magnesium supplements. I know magnesium should also provide relaxation, possibly by antagonizing NMDA receptors in the brain. This led me to try magnesium threonate, which supposedly is the only form of magnesium that crosses the blood brain barrier, and as such it should have a more significant CNS effect compared to other forms of magnesium because it actually can get to the brain.

I used the brand Smart Mag (made in the USA, rare to find) which has the advantage of combining magnesium threonate with magnesium glycinate (which I already know is good) and magnesium taurate (which is also supposed to have a calming effect more than other forms of magnesium because of the taurine), which sounds like the ultimate magnesium combination. This magnesium supplement seems to have a mild anti-anxiety effect and to improve my sleep a little bit. It's nothing like taking a benzodiazepine or other sedatives, it just seems to induce a calmer state.

I also recently started taking MagTabSR, which is a slow-release tablet that supposedly has excellent bioavailability. Too soon to pass judgement on it. I really like the extended release aspect, so I don't have to keep taking magnesium throughout the day, but I'm not crazy about some of the other filler ingredients.

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From user Carl Magnesium oxide is a cheap and poorly bioavailable form of magnesium.

I use Magnesium carbonate exclusively because it is cheap and versatile. It can be reacted with acids to form magnesium salts which are highly absorbable. It could be reacted with citric acid to form magnesium citrate. Malic acid to form magnesium malate. Ascorbic acid to form magnesium ascorbate and so on. It's about 28% magnesium by weight and as I mentioned it is fairly inexpensive. I have several Kg of it ready to use.

As mentioned previously some forms of magnesium can have a laxative effect, magnesium citrate can do this with me so I avoid it. I mainly mix mag carb with a number of acids which neutralizes the acidity and prevents any reaction. A little warm water speeds up the reaction and makes it fizz and turn clear after the reaction is complete.

From: PhoenixRising user Carl on 'Types of Magnesium' <a href="http://forums.phoenixrising.me/index.php?threads/types-of-magnesium.51094/">http://forums.phoenixrising.me/index.php?threads/types-of-magnesium.51094/</a>

Magnesium oxide is a cheap and poorly bioavailable form of magnesium.