report on stroke rehab
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Main Overview
1 Brain Regions and Specific Classes/Systems
Signaling
Parents
+1 Neuroinflammation
1 Brain Regions and Specific Classes/Systems
Metabolic Changes from TBI
Children
10 Peptides and Neuropeptides
1a Decreases in Sphingolipid, glycosphingolipid, phospholipid, purine, microbiome aromatic amino acid and branch chain amino acid metabolites, as well as in flavine adenine nucleotide (FAD) and lathosterol
4 Cholinergic
Acetylcholine/Citicoline and signaling
Cholinergic anti-inflammatory pathway
Cytokines and Chemokines
Dysregulation of acetylcholine and adrenergic signalling
Glucocorticoid Signaling
Neurons
Neuropeptides (Vasoactive neuropeptides (VNs) such as PACAP and VIP have critical roles as neurotransmitters, vasodilators including perfusion and hypoxia regulators, and immune and nociception modulators)
Neurosteroidal Systems
normal resolution of the inflammatory process by NF-κB activation and apoptotic induction is impaired
Receptors
The AMP-activated protein kinase (AMPK) signaling pathway