Orthostatic intolerance (OI)
<p>Fom: 'Chronic Fatigue Syndrome, A Roadmap for Testing and Treatment' <a href="https://sites.google.com/site/cfstestingandtreatmentroadmap/home">https://sites.google.com/site/cfstestingandtreatmentroadmap/home</a>
OH and NMH are conditions in which your blood pressure drops upon standing. In OH the pressure drop is immediate; in NMH the drop occurs after a long period of time standing, or also sometimes after having an unpleasant or upsetting experience.
Symptoms of OH or NMH include: dizziness or light-headedness, feeling that you are going to faint, blurred vision, confusion, weakness, fatigue, nausea. These symptoms appear within a few seconds or minutes of standing up after you've been sitting or lying down, and will disappear if you sit or lie down for a few minutes.<a href="http://www.nhlbi.nih.gov/health/health-topics/topics/hyp/signs" target="blank" rel="nofollow">1</a>
OH and NMH are types of orthostatic intolerance, where an upright posture (standing up) will trigger symptoms.
Patients with ME/CFS have a high prevalence of neurally mediated hypotension (NMH),<a href="http://www.ncbi.nlm.nih.gov/pubmed/9790477" target="blank" rel="nofollow">1</a> which is due to a dysfunction of the autonomic nervous system. In some cases ME/CFS patients can experience almost complete resolution of their ME/CFS symptoms once their NMH is treated.<a href="http://www.ncbi.nlm.nih.gov/pubmed/7674527" target="_blank" rel="nofollow">1</a>
OH is also called:
Postural hypotension
NMH is also called:
Neurally mediated syncope
Neurocardiogenic syncope</p>
<p>From: PhoenixRising user ahimsa on 'pots and orthostatic intolerance, are they the same?' <a href="http://forums.phoenixrising.me/index.php?threads/pots-and-orthostatic-intolerance-are-they-the-same.5241/">http://forums.phoenixrising.me/index.php?threads/pots-and-orthostatic-intolerance-are-they-the-same.5241/</a></p>
<p>Orthostatic intolerance (OI) is the development of a set of characteristic symptoms while standing or sitting upright. It has been associated with chronic fatigue syndrome (CFS) in both adults and children.
The connection between OI and CFS was first introduced in 1995 by Rowe and associates at Johns Hopkins University, who identified a type of OI called neurally mediated hypotension (NMH) in CFS patients. Since 1995, scientists have learned much more about the broader problem of OI in CFS. It is now thought that many CFS patients (up to 97% in some studies) have some form of OI and it seems to be a particular problem in young people and at least with CFS.
Types of OI
There are many types of OI, at least two forms have been linked with CFS in research studies: NMH and postural orthostatic tachycardia syndrome (POTS).
NMH is a precipitous drop (at least 20-25 mm Hg) in systolic blood pressure when standing. The blood pressure drop is accompanied or preceded by an increase in symptoms.
POTS is a rapid increase in heart rate (pulse) of more than 30 beats per minute (bpm) from baseline, or to more than 120 bpm total, during the first 10 minutes of standing. It is also known as chronic orthostatic intolerance, or COI.</p>
<p>Here's another description from <a class="externalLink" href="http://www.nymc.edu/fhp/centers/syncope/orthostatic_intolerance.htm" target="_blank" rel="nofollow">http://www.nymc.edu/fhp/centers/syncope/orthostatic_intolerance.htm</a> :
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<div class="quote">Orthostasis = standing upright. Orthostatic intolerance can then be defined as "the development of symptoms during upright standing relieved by recumbency". Often, illnesses producing orthostatic intolerance include disorders of blood flow, heart rate and blood pressure regulation that, while most easily demonstrable during orthostatic stress, are present in all positions. The term "dysautonomia", signifying autonomic dysfunction, has been frequently applied to this list of disorders, but recent data suggest that autonomic function may be normal in many variants of these conditions but have to cope with unusual circulatory demands. A simple and common example of this is the finding of postural hypotension and postural tachycardia when dehydrated. Therefore it is probably best to denote the type of symptomatic illness by the more vague term "orthostatic intolerance" rather than the more specific term"dysautonomia" which may not be correct. Acute orthostatic intolerance usually manifests as syncope (fainting). Many syncopal patients have no intercurrent illness; between faints they are well.</div>
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<p>One last link to the National Dysautonomia Research Foundation web site - <a href="http://www.ndrf.org/orthostat.htm">http://www.ndrf.org/orthostat.htm</a>
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From: PhoenixRising user glenp on 'pots and orthostatic intolerance, are they the same?' <a href="http://forums.phoenixrising.me/index.php?threads/pots-and-orthostatic-intolerance-are-they-the-same.5241/">http://forums.phoenixrising.me/index.php?threads/pots-and-orthostatic-intolerance-are-they-the-same.5241/</a></p>
<p>It is a good idea to buy your own bp cuff monitor. Take your reading before getting up and after getting up, also check it after standing for a length of time, while sitting and after getting up, keep a diary of your bp and heart rate and take it into the doctor next time you go. If you get an echocardiogram make sure that you get a bubble injection with it. Check out "dysautonomia", its a broader form of this. There is lots of information here on the forums
<a class="externalLink" href="http://www.forums.aboutmecfs.org/showthread.php?4147-Dysautonomia&p=100824#post100824" target="_blank" rel="nofollow">http://www.forums.aboutmecfs.org/showthread.php?4147-Dysautonomia&p=100824#post100824</a></p>