Safety and Tolerability

Several types of adverse safety events have been reported with anti-amyloid therapies, and tolerability is important with any drug treatment. Some of these considerations (which will be expanded in future updates of this algorithm) include:

Safety and Tolerability

• Infusion Related Reactions
• Amyloid Related Imaging Abnormalities
  • Hemorrhage (ARIA-H)
  • Edema (ARIA-E)
• Allergic or anaphylactic reactions
• Expense
• Compliance with dosing schedule
• Compliance with required imaging
• Care partner impact
• Other issues

Stay tuned for future updates on these issues, and their applicability to other forms of dementia treatment.