CNS: central nervous system

<p>also called neonatal HSV meningoencephalitis</p>

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<p>usually presents in the second or third week of life</p>

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<p>Clinical manifestations of neonatal HSV CNS disease include seizures (focal or generalized), lethargy, irritability, tremors, poor feeding, temperature instability, and full anterior fontanel [17,20,21]. Early in the course of HSV CNS disease, none of these signs or symptoms may be apparent.</p>