May be accompanied by:

In the sole report of a herpangina outbreak among young adults requiring hospitalization, fever (96 percent) and sore throat (96 percent) were the most frequent symptoms, followed by headache (72 percent), pain and stiffness of the neck (72 percent), pain and stiffness of the back (65 percent), nausea (50 percent), anorexia (46 percent), and abdominal colic (46 percent)