Neonatal cold injury

<p>Neonatal cold injury following severe hypothermia may be manifested as refusal to eat, apathy and/or edema, and thrombocytopenia; the latter worsens during rewarming [66,67]. Massive pulmonary hemorrhage and other bleeding occur in patients who die while being rewarmed [68]. The mechanism may be increased sensitivity of rewarmed hypothermic platelets to ADP released from erythrocytes, resulting in irreversible platelet aggregation [68].</p>

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