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Thrombocytopenia,Neonatal
Thrombocytopenia,Neonatal,Etiology
Increased Consuption PLTs
Immune TCP
Alloimmune
Alloimmune,Etiology
Parents
Alloimmune
Children
Fetal Platelets Contain an Antigen Inherited from the Father that the Mother Lacks
Mother forms IgG antiplatelet Abs against the "foreign" Ag
Often Develops in the first pregnancy of an at-risk Couple
Risk of severe TCP and IH greater than in autoimmune TCP
Serious Complication: Intracranial Hemorrhage 10-20%