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A Spleen

  1. (anatomy, immunology) In vertebrates, including humans, a ductless vascular gland, located in the left upper abdomen near the stomach, which destroys old red blood cells, removes debris from the bloodstream, acts as a reservoir of blood, and produces lymphocytes.
  2. (archaic, except in the set phrase "to vent one's spleen") A bad mood; spitefulness.
  3. (obsolete, rare) A sudden motion or action; a fit; a freak; a whim.
  4. (obsolete) Melancholy; hypochondriacal affections.
  5. A fit of immoderate laughter or merriment.
Synonyms

milt (now chiefly of animals); lien (uncommon)