Hypocoagulability

<p><em>Wikipedia:</em></p>

<p><em>Hypocoagulability</em> is a bleeding diathesis caused by <a title="Coagulopathy" href="https://en.wikipedia.org/wiki/Coagulopathy">coagulopathy</a>.</p>

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<p>While there are several possible causes, they generally result in excessive bleeding and a lack of clotting.</p>

<h4>Acquired</h4>

<p>Acquired causes of coagulopathy include anticoagulation with warfarin, liver failure, Vitamin K deficiency and disseminated intravascular coagulation.</p>

<p>Additionally, the haemotoxic venom from certain species of snakes can cause this condition, for example Bothrops, rattlesnakes and other speciesof viper. Viral hemorrhagic fevers include dengue hemorrhagic fever and Dengue Shock Syndrome</p>

<p>Leukemia may also cause coagulopathy.</p>

<h4>Autoimmune causes of acquired coagulation disorders</h4>

<p>There are autoimmune causes of coagulation disorders. They include acquired antibodies to coagulation factors, termed inhibitors of coagulation. The main inhibitor is directed against clotting Factor VIII. Another example is <a title="Antiphospholipid syndrome" href="https://en.wikipedia.org/wiki/Antiphospholipid_syndrome">antiphospholipid syndrome</a> an autoimmune, hypercoagulable state.</p>

<h4>Genetic</h4>

<p>Some people lack genes that typically produce the protein coagulation factors that allow normal clotting. Various types of Hemophilia and von Willebrand disease are the major genetic disorders associated with coagulopathy.</p>

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