Kombucha
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The Science of Kombucha
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Uses
To treat atherosclerosis (hardening of arteries)
Scientific evidence is lacking to back this claim.
To treat cancer
Animal studies have shown that kombucha has antioxidant effects, but human studies are lacking.
To treat diabetes
No scientific evidence supports this use in humans.
To treat AIDS
This claim is not backed by research.
To lower blood pressure
No scientific evidence supports this use in humans.
To stimulate the immune system
Animal studies demonstrate immune-stimulating activity, but there is no evidence to support this use in humans.
Clinical Summary
Prepared by fermenting sweetened black tea with a symbiotic culture of bacteria and yeasts (SCOBY), kombucha tea has been used to treat a wide variety of symptoms as well as certain diseases such as cancer, AIDS, and diabetes . The high caffeine and sugar content of the tea may account for increased energy some users have reported following consumption of the product . In vitro and animal studies show potent antioxidant, immunostimulating , hypolipidemic, and hepatoprotective effects with limited toxicity , but clinical studies in humans are lacking.
Because of the fermentation process, kombucha can easily become contaminated. Allergic reactions, jaundice, serious illness, and occasionally death have been associated with the consumption of home-grown kombucha tea . It may also reduce the absorption of drugs that are sensitive to stomach pH levels.
Mechanism of Action
Preparation of kombucha tea yields a slightly carbonated, acidic, fermented drink. Antimicrobial activity against a large number of pathogenic microorganisms even at neutral pH and after denaturation have been demonstrated. This suggests that kombucha contains antimicrobial compounds other than acetic acid and large proteins . In addition, kombucha tea has been shown to have high levels of B vitamins .
Because of the method of culture, it is easy for kombucha to become contaminated with other organisms. Contamination with anthrax and Aspergillus , a fungus that is dangerous to people with lowered immune systems, have been reported.Green tea can stimulate the fermentation process better than black tea; however, it is generally not used.
From Wikipedia:
Kombucha is a variety of fermented, lightly effervescent sweetened black or green tea drinks that are commonly intended as functional beverages for their supposed health benefits. Kombucha is produced by fermenting tea using a "symbiotic 'colony' of bacteria and yeast" (SCOBY). Actual contributing microbial populations in SCOBY cultures vary, but the yeast component generally includes Saccharomyces (a probiotic fungus) and other species, and the bacterial component almost always includes Gluconacetobacter xylinus to oxidize yeast-produced alcohols to acetic and other acids.
The geographic origin of kombucha is unknown and its etymology is uncertain. Historically, kombucha has been home-brewed or locally brewed, but in the late 1990s, commercially bottled kombucha became available in North American retail stores. It is known in Chinese as chájūn (Chinese: 茶菌), Japanese as kōcha-kinoko (紅茶キノコ?), Korean ashongchabeoseotcha (홍차버섯차), Vietnamese as giam tra (giấm trà) and Russian as chaynyy grib (чайный гриб). These names translate literally to "tea fungus" or "tea mushroom."
Kombucha has been claimed to have various health benefits, but there is little evidence to support such claims. There are several documented cases of serious adverse effects, including fatalities, related to kombucha drinking, possibly arising from contamination during home preparation. Since the mostly unclear benefits of kombucha drinking do not outweigh the known risks, it is not recommended for therapeutic use.
Health claims
Kombucha has been promoted with claims that it can treat a wide variety of human illnesses, including AIDS, cancer, and diabetes, and that it provides other beneficial effects such as stimulation of the immune system, boosting the libido, and reversal of gray hair. However, evidence of kombucha's beneficial effects in humans is absent.
In a 2003 systematic review, Edzard Ernst characterized kombucha as an "extreme example" of an unconventional remedy because of the great disparity between implausible, wide-ranging health claims lacking evidentiary support, and the potential for harm the preparations seem to hold. Ernst concluded that the unsubstantiated list of proposed therapeutic benefits did not outweigh the known risks, and that kombucha should not be recommended for therapeutic use.
Adverse effects
Reports of adverse effects related to kombucha consumption are rare. It is unclear whether this is because adverse effects are rare, or just underreported. TheAmerican Cancer Society says that "Serious side effects and occasional deaths have been associated with drinking Kombucha tea".
Adverse effects associated with kombucha consumption include severe hepatic (liver) and renal (kidney) toxicity as well as metabolic acidosis.[8][9][10] At least one person is known to have died after consuming kombucha, though the drink itself has never been conclusively proved a cause of death.[11][12]
Some adverse health effects may be due to the acidity of the tea, which can cause acidosis, and brewers have been cautioned to avoid over-fermentation.[13][14]Other adverse health effects may be a result of bacterial or fungal contamination during the brewing process.[14] Some studies have found the hepatotoxin usnic acid in kombucha, although it is not known whether the cases of damage to the liver are due to the usnic acid contamination or to some other toxin.[9][15]
Topical use of the tea has been associated with anthrax infection on the skin in one report, but kombucha contamination may have occurred during storage.[2]
Due to its microbial sourcing and possible non-sterile packaging, kombucha is not recommended in people with poor immune function,[3] in women who are pregnant or nursing, or in children under 4 years old.[14]
Other uses
Kombucha culture, when dried, becomes a leather-like textile known as a microbial cellulose that can be molded onto forms to create seamless clothing.Using different broth mediums such as coffee, black tea, and green tea to grow the kombucha culture results in different textile colors, although the textile can also be dyed using plant-based dyes. Different growth mediums and dyes also change the textile's feel and texture.The kombucha textile is similar to cellulose and is sustainable and compostable. In 2014, one designer debuted a clothing collection made entirely out of kombucha textile.
Composition and properties
Biological

Yeast and bacteria in kombucha at 400X
A kombucha culture is a symbiotic culture of bacteria and yeast (SCOBY), similar to mother of vinegar, containing one or more species each of bacteria and yeasts, which form a zoogleal mat known as a "mother. The cultures may contain one or more of the yeasts Saccharomyces cerevisiae, Brettanomyces bruxellensis, Candida stellata, Schizosaccharomyces pombe, and Zygosaccharomyces bailii.
The bacterial component of kombucha comprises several species, almost always including Gluconacetobacter xylinus (G. xylinus, formerly Acetobacter xylinum), which ferments alcohols produced by the yeasts into acetic and other acids, increasing the acidity and limiting ethanol content. The population of bacteria and yeasts found to produce acetic acid has been reported to increase for the first 4 days of fermentation, decreasing thereafter G. xylinumhas been shown to produce microbial cellulose, and is reportedly responsible for most or all of the physical structure of the "mother", which may have been selectively encouraged over time for firmer (denser) and more robust cultures by brewers.
In Chinese, the microbial culture producing kombucha is called jiaomu in Mandarin and haomo in Cantonese, meaning, literally, "fermentation mother" (Chinese: 酵母).
The mixed, presumably symbiotic culture has been further described as being lichenous, in accord with the reported presence of the known lichenous natural product usnic acid, though as of 2015, no report appears indicating the standard cyanobacterial species of lichens in association with Kombucha fungal components.
Chemical
Sucrose is converted, biochemically, into fructose and glucose, and these into gluconic acid and acetic acid, and these substances are present in the drink. In addition, kombucha contains enzymes and amino acids, polyphenols, and various other organic acids; the exact quantities of these items vary between preparations. Other specific components include ethanol (see below), glucuronic acid, glycerol, lactic acid, usnic acid (a hepatotoxin, see above), and B-vitamins. Kombucha has also been found to contain vitamin C.
The alcohol content of the kombucha is usually less than 1% but increases with fermentation time.
History
The exact origination of kombucha, how or where, is unknown. The drink was consumed in east Russia at least as early as 1900, and from there entered Europe.In 1913, kombucha was first mentioned in German literature. At least as early as the mid-1990s it became popular in the US.
Etymology

A SCOBY used for brewing kombucha.
The English word is kombucha and has around 80 other names around the world. The Japanese name for what English speakers know as kombucha is kōcha kinoko (紅茶キノコ, literally, "black tea mushroom"), compounding kōcha (紅茶, "black tea") and kinoko (茸, "mushroom; toadstool"). In Japan, Konbucha (昆布茶?, "kelp tea") refers to a different beverage made from dried and powdered kombu (an edible kelp from the Laminariaceae family).
Kombucha is of uncertain etymology. The American Heritage Dictionary suggests that it is probably from the "Japanesekombucha, tea made from kombu (the Japanese word for kelp perhaps being used by English speakers to designate fermented tea due to confusion or because the thick gelatinous film produced by the kombucha culture was thought to resemble seaweed)."
A 1965 mycological study called kombucha "tea fungus" and listed other names: "teeschwamm, Japanese or Indonesian tea fungus, kombucha, wunderpilz, hongo, cajnij, fungus japonicus, and teekwass". Some further spellings and synonyms include combucha and tschambucco, and haipao, kargasok tea, kwassan, Manchurian fungus or mushroom, spumonto, as well as the misnomers champagne of life, and chai from the sea.
Production
Commercially bottled kombucha became available in the late 1990s. In 2010, elevated alcohol levels were found in many bottled kombucha products, leading retailers including Whole Foods to temporarily pull the drinks from store shelves. In response, kombucha suppliers reformulated their products to have lower alcohol levels. By 2014 US sales of bottled kombucha were $400 million; $350 million of that was earned by Millennium Products, Inc. which sells "GT's Kombucha". In 2014, the market was projected to have 30% growth, and companies that make and sell kombucha formed a trade organization, Kombucha Brewers International.
The yeast spectrum of the ’tea fungus Kombucha’.
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Glucuronic acid and gluconic acid are fermentation products in Kombucha tea.
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Kombucha Tea-associated microbes remodel host metabolic pathways to suppress lipid accumulation.

