Bisphenol AF

Bisphenol AF and bisphenol B exert higher estrogenic effects than bisphenol A.

Bisphenol AF blocks Leydig cell regeneration from stem cells in male rats.

BPA alternatives induce similar toxic and estrogenic effects to BPA and that BPAF is more potent than BPA.

Bisphenol AF (BPAF) is a fluorinated organic compound related to bisphenol A in which the two methyl groups are replaced with trifluoromethyl groups.

Whereas BPA binds with human estrogen-related receptor gamma (ERR-γ), BPAF all but ignores ERR-γ. Instead, BPAF activates ERR-α and binds to and disables ERR-β