Tomatoes / Tomato, Studies

• A review of the health benefits of tomato compounds to help prevent or treat human disease.
• Carotenoid absorption in humans consuming tomato sauces obtained from tangerine or high-beta-carotene varieties of tomatoes.
• Exploring the Effects of Selenium Treatment on the Nutritional Quality of Tomato Fruit
• Home processing of tomatoes (Solanum lycopersicum): effects on in vitro bioaccessibility of total lycopene, phenolics, flavonoids, and antioxidant capacity.
• Arbuscular mycorrhizal fungal inoculation increased the antioxidant capacity and nutrient quality of tomato fruits for most nutrients except vitamins.
• A water extract from spent mushroom substrate of Hericium erinaceus suppresses bacterial wilt disease in Tomatoes.

Anti-inflammatory

• Tomatoes may have the potential to suppress inflammation by inhibiting the production of NO or proinflammatory cytokines during the interaction between adipocytes and macrophages.

Antioxidant

Tomato juice has a potential antioxidant effect and may reduce the elevated level of ROS induced by oxidative stress.

Cancer

• The tomato diet significantly inhibited TNFα stimulated NF-κB activity in cultured PC3 cells, and modulated the expression of genes associated with inflammation, apoptosis, and cancer progression.
• Dietary tomato components reduced testosterone regulated genes associated with early prostate carcinogenesis.
• This study supports the hypothesis that a diet rich in tomato and broccoli can reduce or prevent dietary carcinogen induced cancers.

Cardiovascular

• Tomato-based food products are related to clinically modest improvements in selected coronary biomarkers in women.
• In-season consumption of locally produced tomatoes decreases cardiovascular risk indices.

Depression

Antidepressant-like effects of tomatidine and tomatine, steroidal alkaloids from unripe tomatoes.

Gastrointestinal Effects

• Effect of water-soluble fraction of cherry tomatoes on the adhesion of probiotics and Salmonella to intestinal epithelial cells.
• Tomato lectin binds selectively to the small intestine epithelium and undergoes uptake through gut associated lymphoid tissue (GALT) and through normal enterocytes.

Hepatoprotective

• Tomato powder could be an effective whole food prevention strategy against alcoholic liver disease.
• Tomato extract supplementation decreases hepatic inflammation and plasma total cholesterol associated with high dietary fat intake.
• Probiotic-fermented tomato with hepatic lipid metabolism modulation effects.
• Red and golden tomato administration improves fat diet-induced hepatic steatosis.

Neuroprotective

Guava and Tomato Lower Risks for Neurodegenerative Diseases

Post-Menopause

Supplementation with beefsteak tomato before sleep can increase circulating melatonin and improve sleep quality in obese postmenopausal women.

Obesity

• Increasing tomato intake may provide a useful approach for reducing the risk of inflammatory diseases such as CVD and diabetes, which are associated with obesity.
• Scientists document at the anti-obesity effects of tomato and broccoli
• Lycopene and tomato powder supplementation similarly inhibit high-fat diet induced obesity, inflammatory response, and associated metabolic disorders.

Radiation

A 10% Tomato Diet Selectively Reduces Radiation-Induced Damage in TRAMP Mice