Styrylpyrones

Any styryl derivative of a pyrone, some of which show anticancer activity

A small group of phenolic compounds biosynthetically descended from cinnamic acid (the parent compound of the phenylpropanoids). So far, they have only been found in plants of the Lauraceae and Piperaceae families. In the later group we have the important medicinal social/ritual herb, Kava (Piper methysticum). The specific styrylpyrones in this plant are called either kavalactones or kavapyrones; both names apply since the lactone ring (which is also a pyrone ring) is the common feature. The kavalactones include kavain (antispasmodic, anti-inflammatory, anti-edemic), methysticin, and yangonin (both antispasmodic). These compounds have low solubility in water and are usually extracted with high-percentage ethanol or with organic solvents like acetone. Traditionally they were extracted in fat-rich Coconut milk. (-Ganora)

• Styrylpyrone-class compounds from medicinal fungi Phellinus and Inonotus spp., and their medicinal importance
• Neolignans, styrylpyrones and flavonoids from an Aniba species
• Styrylpyrone biosynthesis in Equisetum arvense
• Styrylpyrones from the medicinal fungus Phellinus baumii and their antioxidant properties

Antifungal

Antifungal Enantiomeric Styrylpyrones from Sanrafaelia ruffonammari and Ophrypetalum odoratum.