Manaca
Medicinal Parts: the roots and stem
Constituents
Active ingredients have not yet been adequately investigated. The spasmogenic brunfelsamidine, identical with Nierembergia toxin, has been demonstrated in the related species Brunfelsia grandiflora
Effects
Diuretic and antirheumatic effects have been attributed to Manaca.
Uses
Used in the treatment of rheumatic conditions.
Liquid extracts are provided for internal use.
Physio-Medical Therapeutics, Materia Medica and Pharmacy BY T. J. LYLE, A.M.M. 1897
In Brazil, manaca is regarded as a specific for the cure of rheumatic affections. The results obtained have been good. The fluid extract may be used or the elixir which combines also the virtues of the salycilates of sodium, potassium and lithium, and is hence valuable in the treatment of lithic diathesis.
Cautions
No health hazards or side effects are known in conjunction with the proper administration of designated therapeutic dosages. In animal experiments, anxiety sttes, restlessness, increase in cardiac and pulmonary frequency, elevated salivation, vomiting, muscle tremors and tonic-clonic spasms were observed following intake of plant parts of Brunfelsia species, as well as death.