Mannitol

Found in Kelp and occurs naturally as the main constituent of “manna” an edible exudate from some species of Ash (Fraxinus) Its sometimes used in phytotherapy to treat constipation and to simulate the gallbladder. In food technology, synthetically-produced mannitol is used similarly to sorbitol. It also has numerous medical and pharmaceutical uses.

Mannitol may be useful clinically both as a diuretic and as an obligate extracellular solute. As a diuretic it can be used to treat patients with intractable edema states, to increase urine flow and flush out debris from the renal tubules in patients with acute tubular necrosis, and to increase toxin excretion in patients with barbiturate, salicylate or bromide intoxication. As an obligate extracellular solute it may be useful to ameliorate symptoms of the dialysis disequilibrium syndrome, to decrease cerebral edema following trauma or cerebrovascular accident, and to prevent cell swelling related to renal ischemia following cross-clamping of the aorta. Largely unexplored uses for mannitol include its use as an osmotic agent in place of dextrose in peritoneal dialysis solutions, its use to maintain urine output in patients newly begun on hemodialysis, and its use to limit infarct size following acute myocardial infarction. Read more...

Mannitol and the blood-labyrinth barrier.

Lactobacillus reuteri CRL 1101 highly produces mannitol from sugarcane molasses as carbon source

Mannitol

Baker's Asthma

Cystic Fibrosis

Gastrointestinal Effects

Hemodialysis

Pulmonary Fibrosis

Renoprotective

Stroke

Traumatic Brain Injury

Other Effects

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