p-Coumaric Acid
p-Coumaric acid is a white solid organic compound that is one of the three isomers of hydroxycinnamic acid. It is a major constituent of lignin, a phenolic polymer in lignocellulosic materials.
It blocks release of pro-inflammatory molecules like cytokines and histamine. It modulates the immune system.
p-Coumaric acid is a plant metabolite that has antioxidant, antimicrobial, antitumor, antiangiogenic, antidiabetic, antihyperlipidemic, neuroprotective, and anti-inflammatory properties. It also has bactericidal activity by damaging bacterial cell membranes and interacting with bacterial DNA.
p-Coumaric acid is also used as an enhancer in chemiluminescent substrate in western blot.
p-Coumaric acid is also known as:
- 2-Propenoic acid, 3-(4-hydroxyphenyl)-
- Cinnamic acid, p-hydroxy-
- β-(4-Hydroxyphenyl)acrylic acid
- p-Hydroxycinnamic acid
- p-Hydroxyphenylacrylic acid
- 4-Coumaric acid
- 4'-Hydroxycinnamic acid
- 3-(4-Hydroxyphenyl)-2-propenoic acid
- NSC 59260
*p*-Coumaric acid kills bacteria through dual damage mechanisms